how to convert spm12 Matlab code to python?

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Spm12 , GUI interface which is built on Matlab compiler.It runs inside Matlab application. Source code is available at https://github.com/spm/spm12

I need to covert the whole application into python language, any suggestions on how to get started on this?

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A good starting point might be to look at what other people have already done. I haven't used nipy personally but colleagues have.

https://nipy.org/

https://nipype.readthedocs.io/en/latest/index.html