Office 365 App connectivity with On-Premise SQL Server Database

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I am new to O365, need help on below scenario:

We have to deploy an office 365 app (custom app) in our corporate Office 365 tenant. This app will communicate with SQL Server database. On-Premise database server sits in corporate virtual network . What firewall changes will be needed to enable this this connectivity?

Do we need to get all ports opened as mentioned on link https://blogs.technet.microsoft.com/educloud/2011/11/30/what-firewall-ports-do-i-need-open-to-connect-to-office-365-for-education/

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The gateway creates an outbound connection to Azure Service Bus.

It communicates on outbound ports: TCP 443 (default), 5671, 5672, 9350 thru 9354.

The gateway doesn't require inbound ports.

For more information, please review the following link: Configure a firewall or proxy