I've never been able to get distcc to work successfully in Fink or MacPorts on my Macs, despite much tweaking and hacking.
I have used distcc successfully on various Linux platforms, as well as on OS X proper.
Has anyone been able to get distcc to distribute compiling among several Macs from within Fink or MacPorts? How about HomeBrew? I'm mainly interested in proof-of-concept: Can it be done?