Using App Engine Datastore over MySQL for a CRM System

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I am about to take on a project, and I will to ask which database is best to use to build and develop a CRM System that does a lot of reporting and calculations for an Advertisement company. My choices are MySQL and the Google App Engine Datastore (NoSQL). Left to me I want to use the Datastore but am concerned about the constant reporting and constant calculations on the CRM System. please advice.. Thanks

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Consider google datastore limits in your analysis:

There is no aggregate functions in datastore, you won't be able to do group by.

Try both (PoC), and you'll find out which fits best your use case.