VS 2103 Cannot Debug asp.net due to Corrupted ScriptResource.axd

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I have been working on a very complex asp.net program and suddenly after 2 years of development I receive the following:

I cannot post the Screen Image where but you can see it at: http://vmcsys.com/images/VSCorruption.jpg)

This happens in VS2012 Professional while starting a debug session. The program runs fine outside using any of the major internet browsers.

I have wiped out the entire directory, downloaded a backup. It seems no matter what I do, I still run into this program. Where is ScriptResource.axd located? Should I reinstall VS2012? I am also using Ajax Toolkit. Any ideas would very much be appreciated. Thanks!

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Solved this by adding the following to Webconfig file

<system.web.extensions>
    <scripting>
      <scriptResourceHandler enableCompression="false" enableCaching="true"/>
    </scripting>
  </system.web.extensions>