Simulation of real world scenario on simulink/simscape

Question

I'm planning on simulating a real world scenario in Matlab. I have an experimental setup inside a closed environment in which the humidity is controlled predominantly. I'm studying the effects of humidity on the machine and see if the output of the machine itself along with the raw material fed into the machine depends on the varying levels of humidity. Is it possible to mimic the same environment in Simulink/Simscape without any test dataset solely depending on the physical equations of the physical parameters and the machine and materials involved? As an example, i can state the working of a machine to extrude plastic resins in a closed environment where the humidity is kept constant at different levels and the efficiency of the extruder at different levels of humidity is calculated based on the experiments. Can i repeat the same in simulink/simscape by setting up the same model? My aim would be to compare the real world scenario with the matlab model. I would be grateful to get some expert opinions/help/answers inside the stackoverflow community. Thank you!