I'm wondering how to speed up picard's SortSam? It takes a long time to run it and I know GATK can be multi-threaded but I have not found example on Picard yet.
I'm wondering how other people tackle this problem?
Picard SortSam speed up?
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Unfortunately, sorting a random BAM file can't be speed up due to the nature of the problem. That's why the tool doesn't offer multithreading.